American whaler George departed to sea in 1818

Of Nantucket, master John Fitch, departed on 10 November 1818 towards the Pacific Ocean and returned on 19 May 1821 with 2.135 barrels sperm and 25 barrels whale.

Source
Catalogue of Nantucket Whalers and their voyages from 1815 to 1870. Hussey&Robinson, Nantucket, 1876.