American whaler Lady Adams departed to sea in 1820

Of Nantucket, master Shubaek Hussey, departed on 28 February to the Pacific Ocean, returned on 17 October 1821 1.136 barrels sperm 80 whale.  

Source

Catalogue of Nantucket Whalers and their voyages from 1815 to 1870. Hussey&Robinson, Nantucket, 1876.